Is it realistically possible to build a successful career in biological research in Italy?

I'm considering a long-term career in neuroscience or genetics research and I'm trying to understand whether Italy can realistically offer the opportunities needed to build an impactful academic career. From your experience, can researchers do internationally competitive work while staying in Italy, or do most eventually need to move abroad because of funding, career progression or research infrastructure? I'm especially interested in hearing from people who have worked both in Italy and abroad.