You should establish personal and professional goals. That said, it depends on what makes you happy and fulfills you. It would be different for everyone. For example, I have goals surrounding philanthropy and how I want to "give back" to my local and global community. Giving back can be by volunteering or monetarily. I also have goals to ensure that I have a work life/personal life balance. You need to ensure that you are working to live and not living to work. If you don't have balance in your life and focus all of your energy on your career you will burn out and find that many of the things you worked towards don't matter if you have noone to share them with.