Hi Emily! I am a recent graduate of a Big 10 University and large classes can be a real challenge! I would recommend trying to take some of the large lecture classes in your sophomore and junior year. I found it helpful with the college transition to take the smaller size classes in my freshman year. That being said, college scheduling can be really challenging and you might be like me and end up in a Calculus class with 300+ people your first semester of college. If you are feeling overwhelmed or nervous about a large class size definitely meet with the professor. He/she can help connect you with TAs and other students in the lecture! There is no doubt that large classes can be tough but try to connect with others and the class will feel much more comfortable.