I have had the opportunity to hire hundreds of people spanning a career of more than 35 years. For this specific question I’ll assume we are discussing an entry level position. First you begin building a resume in high school and on through college. You need to not only complete course work that is somewhat relevant to the job you are applying for but also exhibit a well rounded interest in other classes and topics. Possibly the most important item is to be able to talk about projects and community service that you have completed. Finally when u get that first interview; be prepared, study up on the company, ask questions and above all else act like you are interested and want the job.