Great question!! Note taking is a large part of college and you will spend the majority of your time in lecture classes taking notes on what the professor says. Because of this, it is really important that you develop a method that allows you to take the best notes possible. I personally found that I was best able to take notes via paper and pencil. Many professors allow you to bring your laptop to class but this is a total trap. Most people who brought in their laptop would be on Facebook, YouTube, or Twitter during class and really would be neither focused on what the professor was saying nor would take good notes. It's just too tempting to look at funny cat videos instead of paying attention to what is being said in class. After my first year of school I would always leave my laptop at home and would bring my notebook to class.
Hand writing notes is really great as the process of writing things down is proven to enable better retention of information. There is something with writing things down that allows your brain to retain that information longer than if you were to type your notes. Also, since there is no way that you can write down everything the professor says you will be forced to write only the most important things that are said. It is really easy to type everything that the professor says but this does you no help and you will just end up having pages and pages of notes with no idea what is important. My hand would definitely get tired writing things down and trying to keep up with the professor, but I would always come out of class with a few pages of top-notch notes instead of a novel of typed notes.
Also, try and develop a system of shorthand for your notes. Because hand writing is slow, I developed my method of shorthand and acronyms to aid me in taking notes. For example:
Intl= International WWII= World War Two
C=China CvJW= Sino-Japanese War
J=Japan C'sD change: S-->Z-->Q= China's Dynastic Change: Shang, Zhou, Qin
(I think you get an idea of what I studied in College)
I hope this helps and I wish you the best of luck!!