It's definitely ok to choose a major that you think has limited opportunities where you live, but if that's the case, it's probably a good idea to be open to moving to find a position after college. Even though fashion jobs are probably more limited in Ohio than other states, there are still a number of opportunities in Ohio that you might find interesting. For instance, did you know that L Brands is headquartered in Columbus, Ohio? L Brands is the company that owns companies such as Victoria's Secret, Pink, and Bath & Body Works. Abercrombie & Fitch and DSW also have a strong presence in central Ohio. It may be helpful to do some online searched and see what companies are around the area you live. You can also search job posting to see what kinds of opportunities would be available to you upon graduating.
While in college, you have a great opportunity to look for internships and positions that help you gain experience in a field that interests you, and also test the fields out to see if it's a good fit for you. It sounds like you're already in college, so you have a lot of great resources available to you. Talk with your professors and ask if they can connect you to former students or alumni that they know who could give you advice on how to get into your field of interest without having to relocate. However, if you do find that you'd need to relocate, it could be a great opportunity to have an adventure and live in a city you would have otherwise never experienced! Keep your mind open to different possibilities and make sure you follow your gut!