I assume you mean the adjustment from high school to college--the adjustment is different for everyone since a lot of it is due to personality and individual circumstances. For example, are you someone that likes to plan ahead? Are you someone who is naturally a good student? Are you someone who thrives with a strong social network?
The fact that you're asking this question now means you are looking ahead, which is great! The next step is to do some self-reflection on your strengths and weaknesses. Find ways to utilize those strengths in college. For example, if you know you are a social butterfly, use that ability to network and make friends by joining lots of clubs and organizations. Also do some research into how to help improve your weaknesses. For example, if you know you aren't great at studying, research into resources like free tutoring or study groups at your university to give you more support in this area.
I would also recommend finding a mentor. Depending on your college, there should be some kind of mentoring program in place. Talk to your academic advisor/counselor and see if they can connect you with someone who can give you well-rounded support and answer your questions about adjusting to college.