How to get from PharmD to bench work drug synthesis?

As a high school senior, my current plan is to enter a 6 year PharmD program, then either go into a fellowship or a PhD program (in Organic Chemistry, perhaps) to secure the relevant qualifications for the R&D work I want to do. However, I'm very hesitant about the PharmD portion, as I am currently not enthusiastic about the clinical work it would entail. The real reason I want the degree is for security---if research ends up being too unstable, or if I need to take a break from education for any reason, clinical pharmacy seems like a good option financially and stability-wise. But as it stands, I really can't see myself doing it as a career---that simply isn't where my passion lies. So firstly: Does this plan make sense? Could someone with an educational background like the one I described be marketable to big pharma for research? If so, would someone with a PharmD (who has a heavy Organic Chem focus through electives, undergrad research, internships and summer programs, etc.) be marketable to PhD or fellowship programs in the realm of drug synthesis? Would it be possible to acquire the relevant experience to make it so, or would that pursuit conflict too strongly with pharmacy coursework/residency? Are there other, perhaps more straightforward ways to make it to the R&D roles I want, while still offering more secure and well-paying job options (without clinical focus, ideally)?